ADHD Disease

About Gene:

ADHD, is a neurodevelopment disorder that typically shows symptoms from childhood. Patients tend to have difficulty focusing and controlling impulsive behavior.

Number of Patients: 0

Disease Causing Genes:

RBFOX1 YWHAZ PDX1 BDNF PAWR LIG4 COMT SLC6A4 MTHFR PTPRD IL6 ATP8B1 FZD7 DRD2 MMP9 SLC6A3 NR3C1 DRD4 DHODH CDH13 MAOA TERT HTR2A SIRT1 ADH1C CYP2C19 TFEB AMOTL1 CYP2D6 PITRM1 FTO ICAM1 ABHD13 GSK3B ZBTB16 DNM1 IL1RN SLC6A1 KDM4D TPH2 FMR1 PRKN SERPINA1 DRD1 SLC6A2 DRD3 DBH ADRA2A MPO IGF2 SNAP25 OXTR MAP1B NOS1 CNR1 ITGAE CWC15 MC4R PINK1 HTR1B ADORA2A ETV3 CHRNA7 PIK3CG GPR85 TXN NGF PKD1L2 MAOB KCNJ11 KIRREL3 HTR1A GPER1 CLOCK ESRRB KIF6 RIT1 PKD1L3 GRIN2B UNC5B RGL1 CDK5 CRYGC NR3C2 DISC1 LRP5 MTRR TPH1 DRD5 THRB GDNF MIR182 MEF2C TH CHRNA4 C5orf15 STS SPATA8 MYT1L ITGA11 TACR1 CHRNA5 LRP6 GAD1 PPM1F ASTN2 CHRNA3 GRIN2A GSX1 CREB5 PER2 GPC6 RUNX1T1 FADS2 STX1A PIWIL4 SUPT3H KCNJ5 BMT2 MIR183 ATP2C2 FOXP2 MTHFD1 ZNF804A PER3 MIR96 NTRK3 NTF3 PTGDS CNTNAP2 HTR3A DDC CES1 PPM1K PPP1R1B ADGRL3 MIR34C MIR185 SLC1A3 DCLK1 ATXN1 NPSR1 REEP5 SYT1 SLC2A3 NSD1 MMP24 MOBP MIR34B MIR26B KDM4A MTNR1A MYRFL SERPINA6 HTR4 VAMP2 GRM7 CHRNB4 C16orf46 SYP KIAA2012 ETV3L PLUT KIAA2012-AS1 HRAT17 LINC02294 LOC101927967 TFAP2B ADRA2C BAIAP2 DCDC2 MFHAS1 MAN2A2 SOX6 RCC1 MIR191 VIPR2 BHMT GFI1 GIT1 TLL2 CFAP43 CAPRIN1 CSMD2 NET1 ICAM2 ADRA1B GRIK1 TRAPPC9 NT5DC3 GNAL NLGN3 CHRNA6 CHRNB3 EPHA5 AK8 TNRC6B CFAP221 TRIM31 ASMT ASMT NMRAL2P ST3GAL3 PPP2R2C LIN7C LIN7A SLC5A4 CHMP7 SORCS3 TARBP1 OBI1 POLR3C DIRAS2 LOC100507443 LIN7B FBXO25 PRTG LRRTM4 RNF122 SNORC STXBP5-AS1 LOC108228198 LOC108228197

Sign and Symptoms:

  1. Impulsivity
  2. Disorganization
  3. Problem priotizing
  4. Problems with focusing
  5. Trouble multitasking
  6. Excessive activity
  7. Restless
  8. Low frustration tolerance

Diagnosis:

(1) Interview (2) Identification of serum level of lead (3) Significant increase of plasma ammonia and lactate

Preventions:

Treatment: