Epidermodysplasia verruciformis Disease

About Gene:

Epidermodysplasia verruciformis (EV) is a rare, genetic skin disorder that is characterized by the development of scaly, wart-like lesions on the skin.

Number of Patients: 1

Disease Causing Genes:

TMC8 TMC6 IL7 CDKN2A CDH1 CIB1 FLG RHOH CD1A CD83 CORO1A

Sign and Symptoms:

  1. Multiple, flat, wart-like skin lesions
  2. Raised, reddish-brown patches
  3. Warts-like lesions on trunk and extremities
  4. Lesions may become thick and scaly
  5. Scaling, itching, and pain

Diagnosis:

(1) Medical history collection (2) Physical examination (3) Biopsy (4) X-ray

Preventions:

Treatment:

1. Avoiding sun exposure: Sun exposure can trigger the lesions to become more severe, so it is important to avoid direct sun exposure and use sunscreen when in the sun. 2. Use of topical medications: Topical medications, such as imiquimod, can be used to reduce the size of the lesions and prevent new lesions from forming. 3. Surgery: In more severe cases, surgery may be recommended to remove the lesions and reduce the risk of skin cancer. 4. Vaccination: HPV vaccination can help to prevent new infections with the virus, which can reduce the risk of developing EV. 5. Regular skin checks: Regular skin