Patients of Noonan’s Syndrome

  • Patient Serial No - 1
  • Age:

    25

    Sex:

    female

    Location:

    dhaka

    Clinical Features:

    • Generalized skin eruptions for 25 days and heavy left leg since childhood. • Eruptions were hyperkeratotic scaly, bilaterally and symmetrically distributed over erythematous base. • Lesions were scaly over dorsum of hands, trunk and neck. • Lesions were pruritic but less severe. • Left leg was edematous; edema 2-plus, localized and pitting type. • Occasional central, continuous, nonradiating chest pain. • Occasional palpitation. • Moderately anemic.

    Biochemical Data:

    Hb level 9.9 g/dl; ESR 30 mm in 1st hr; Urine routine and microscopic examination showed trace amounts of albumin with normal number of epithelial cell and pus cell; Serum IgE 268 IU/ml;

    treatement and management:

    • Topical application of 5% Crotamiton cream and a combination of Hydrocortisone and Fusidic acid ointment • Applied locally over the lesions thrice daily Oral medications: • Tab Desloratadine (5 mg) twice daily • Tab Normanal (500 mg) twice daily for 15 days • Antibiotic Azythromycin (500 mg) once daily for 5 days.